Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein

TRIM28 regulates its target genes at both transcriptional and posttranscriptional levels. Here we report that a TRIM28-TWIST1-EMT axis exists in breast cancer cells and TRIM28 promotes breast cancer metastasis by stabilizing TWIST1 and subsequently enhancing EMT. We find that TRIM28 is highly expres...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Sci Rep
मुख्य लेखकों: Wei, Chunli, Cheng, Jingliang, Zhou, Boxv, Zhu, Li, Khan, Md. Asaduzzaman, He, Tao, Zhou, Sufang, He, Jian, Lu, Xiaoling, Chen, Hanchun, Zhang, Dianzheng, Zhao, Yongxiang, Fu, Junjiang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Nature Publishing Group 2016
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944148/
https://ncbi.nlm.nih.gov/pubmed/27412325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29822
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