Tripartite motif containing 28 (TRIM28) promotes breast cancer metastasis by stabilizing TWIST1 protein

TRIM28 regulates its target genes at both transcriptional and posttranscriptional levels. Here we report that a TRIM28-TWIST1-EMT axis exists in breast cancer cells and TRIM28 promotes breast cancer metastasis by stabilizing TWIST1 and subsequently enhancing EMT. We find that TRIM28 is highly expres...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Wei, Chunli, Cheng, Jingliang, Zhou, Boxv, Zhu, Li, Khan, Md. Asaduzzaman, He, Tao, Zhou, Sufang, He, Jian, Lu, Xiaoling, Chen, Hanchun, Zhang, Dianzheng, Zhao, Yongxiang, Fu, Junjiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4944148/
https://ncbi.nlm.nih.gov/pubmed/27412325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29822
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg