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Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function

The human tripartite motif (TRIM) family comprises 70 members, including HIV restriction factor TRIM5α and disease-associated proteins TRIM20 (pyrin) and TRIM21. TRIM proteins have conserved domain architecture but diverse cellular roles. Here, we describe how the C-terminal PRYSPRY domain mediates...

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Detalhes bibliográficos
Main Authors: James, Leo C., Keeble, Anthony H., Khan, Zahra, Rhodes, David A., Trowsdale, John
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1851072/
https://ncbi.nlm.nih.gov/pubmed/17400754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609174104
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