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Structural basis for PRYSPRY-mediated tripartite motif (TRIM) protein function
The human tripartite motif (TRIM) family comprises 70 members, including HIV restriction factor TRIM5α and disease-associated proteins TRIM20 (pyrin) and TRIM21. TRIM proteins have conserved domain architecture but diverse cellular roles. Here, we describe how the C-terminal PRYSPRY domain mediates...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1851072/ https://ncbi.nlm.nih.gov/pubmed/17400754 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609174104 |
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