Antibodies mediate intracellular immunity through tripartite motif-containing 21 (TRIM21)

Antibodies provide effective antiviral immunity despite the fact that viruses escape into cells when they infect. Here we show that antibodies remain attached to viruses after cell infection and mediate an intracellular immune response that disables virions in the cytosol. We have discovered that ce...

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Bibliographic Details
Main Authors: Mallery, Donna L., McEwan, William A., Bidgood, Susanna R., Towers, Greg J., Johnson, Chris M., James, Leo C.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993423/
https://ncbi.nlm.nih.gov/pubmed/21045130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014074107
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