5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells()

Plants of the Amaryllidaceae family produce a large variety of alkaloids and non-basic secondary metabolites, many of which are investigated for their promising anticancer activities. Of these, crinine-type alkaloids based on the 5,10b-ethanophenanthridine ring system were recently shown to be effec...

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Veröffentlicht in:Eur J Med Chem
Hauptverfasser: Henry, Sean, Kidner, Ria, Reisenauer, Mary R., Magedov, Igor V., Kiss, Robert, Mathieu, Véronique, Lefranc, Florence, Dasari, Ramesh, Evidente, Antonio, Yu, Xiaojie, Ma, Xiuye, Pertsemlidis, Alexander, Cencic, Regina, Pelletier, Jerry, Cavazos, David A., Brenner, Andrew J., Aksenov, Alexander V., Rogelj, Snezna, Kornienko, Alexander, Frolova, Liliya V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943583/
https://ncbi.nlm.nih.gov/pubmed/27218860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.05.004
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