5,10b-Ethanophenanthridine amaryllidaceae alkaloids inspire the discovery of novel bicyclic ring systems with activity against drug resistant cancer cells()

Plants of the Amaryllidaceae family produce a large variety of alkaloids and non-basic secondary metabolites, many of which are investigated for their promising anticancer activities. Of these, crinine-type alkaloids based on the 5,10b-ethanophenanthridine ring system were recently shown to be effec...

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Pubblicato in:Eur J Med Chem
Autori principali: Henry, Sean, Kidner, Ria, Reisenauer, Mary R., Magedov, Igor V., Kiss, Robert, Mathieu, Véronique, Lefranc, Florence, Dasari, Ramesh, Evidente, Antonio, Yu, Xiaojie, Ma, Xiuye, Pertsemlidis, Alexander, Cencic, Regina, Pelletier, Jerry, Cavazos, David A., Brenner, Andrew J., Aksenov, Alexander V., Rogelj, Snezna, Kornienko, Alexander, Frolova, Liliya V.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943583/
https://ncbi.nlm.nih.gov/pubmed/27218860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2016.05.004
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