Antiproliferative Activity of 2,3-Disubstituted Indoles Toward Apoptosis-Resistant Cancers Cells

Many types of cancer, including glioma, melanoma, NSCLC, among others, are resistant to apoptosis induction and poorly responsive to current therapies with propaptotic agents. We describe a series of 2,3-disubstituted indoles, which display cytostatic rather than cytotoxic effects in cancer cells, a...

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Detalhes bibliográficos
Main Authors: Magedov, Igor V., Lefranc, Florence, Frolova, Liliya V., Banuls, Laetitia Moreno Y, Peretti, Amanda S., Rogelj, Snezna, Mathieu, Véronique, Kiss, Robert, Kornienko, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3915534/
https://ncbi.nlm.nih.gov/pubmed/23622980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2013.03.110
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