Llwytho...

Unprecedented C-2 Arylation of Indole with Diazonium Salts: Syntheses of 2,3-Disubstituted Indoles and their Antimicrobial Activity

A novel reaction of indole with aryldiazonium salts leading to the formation of 2-aryl-3-(arylazo)indoles was discovered. The products were found to possess potent anti-MRSA and anti-LLVRE activities. The SAR studies indicate that the potentially metabolically labile azo functionality can be replace...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Daly, Seth, Hayden, Kathryn, Malik, Indranil, Porch, Nikki, Tang, Hong, Rogelj, Snezna, Frolova, Liliya, Lepthien, Katrina, Kornienko, Alexander, Magedov, Igor V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233240/
https://ncbi.nlm.nih.gov/pubmed/21752646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2011.06.081
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