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Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin.

To determine in vivo functional roles for thrombin's structural domains, we have compared the relative antithrombotic and antihemostatic effects of (i) catalytic-site antithrombin peptide, D-Phe-Pro-Arg; (ii) exosite antithrombin peptide, the C-terminal tyrosine-sulfated dodecapeptide of hirudi...

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Dades bibliogràfiques
Autors principals: Kelly, A B, Maraganore, J M, Bourdon, P, Hanson, S R, Harker, L A
Format: Artigo
Idioma:Inglês
Publicat: 1992
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC49433/
https://ncbi.nlm.nih.gov/pubmed/1385867
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