Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin.

To determine in vivo functional roles for thrombin's structural domains, we have compared the relative antithrombotic and antihemostatic effects of (i) catalytic-site antithrombin peptide, D-Phe-Pro-Arg; (ii) exosite antithrombin peptide, the C-terminal tyrosine-sulfated dodecapeptide of hirudin; an...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Kelly, A B, Maraganore, J M, Bourdon, P, Hanson, S R, Harker, L A
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1992
Matèries:	Research Article
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1385867/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.13.6040
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