Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin.

To determine in vivo functional roles for thrombin's structural domains, we have compared the relative antithrombotic and antihemostatic effects of (i) catalytic-site antithrombin peptide, D-Phe-Pro-Arg; (ii) exosite antithrombin peptide, the C-terminal tyrosine-sulfated dodecapeptide of hirudi...

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Bibliografiska uppgifter
Huvudupphovsmän: Kelly, A B, Maraganore, J M, Bourdon, P, Hanson, S R, Harker, L A
Materialtyp: Artigo
Språk:Inglês
Publicerad: 1992
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC49433/
https://ncbi.nlm.nih.gov/pubmed/1385867
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