Identification of human viral protein-derived ligands recognized by individual MHCI-restricted T-cell receptors

Evidence indicates that autoimmunity can be triggered by virus-specific CD8(+) T cells that crossreact with self-derived peptide epitopes presented on the cell surface by major histocompatibility complex class I (MHCI) molecules. Identification of the associated viral pathogens is challenging becaus...

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Publicado en:Immunol Cell Biol
Autores principales: Szomolay, Barbara, Liu, Jie, Brown, Paul E, Miles, John J, Clement, Mathew, Llewellyn-Lacey, Sian, Dolton, Garry, Ekeruche-Makinde, Julia, Lissina, Anya, Schauenburg, Andrea J, Sewell, Andrew K, Burrows, Scott R, Roederer, Mario, Price, David A, Wooldridge, Linda, van den Berg, Hugo A
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2016
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4943067/
https://ncbi.nlm.nih.gov/pubmed/26846725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2016.12
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