Peptide length determines the outcome of TCR/peptide-MHCI engagement

αβ-TCRs expressed at the CD8(+) T-cell surface interact with short peptide fragments (p) bound to MHC class I molecules (pMHCI). The TCR/pMHCI interaction is pivotal in all aspects of CD8(+) T-cell immunity. However, the rules that govern the outcome of TCR/pMHCI engagement are not entirely understo...

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Xehetasun bibliografikoak
Egile Nagusiak: Ekeruche-Makinde, Julia, Miles, John J., van den Berg, Hugo A., Skowera, Ania, Cole, David K., Dolton, Garry, Schauenburg, Andrea J. A., Tan, Mai Ping, Pentier, Johanne M., Llewellyn-Lacey, Sian, Miles, Kim M., Bulek, Anna M., Clement, Mathew, Williams, Tamsin, Trimby, Andrew, Bailey, Mick, Rizkallah, Pierre, Rossjohn, Jamie, Peakman, Mark, Price, David A., Burrows, Scott R., Sewell, Andrew K., Wooldridge, Linda
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Hematology 2013
Gaiak:
Immunobiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3653566/
https://ncbi.nlm.nih.gov/pubmed/23255554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-06-437202
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