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Leukaemia cell of origin identified by chromatin landscape of bulk tumour cells
The precise identity of a tumour's cell of origin can influence disease prognosis and outcome. Methods to reliably define tumour cell of origin from primary, bulk tumour cell samples has been a challenge. Here we use a well-defined model of MLL-rearranged acute myeloid leukaemia (AML) to demons...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942573/ https://ncbi.nlm.nih.gov/pubmed/27397025 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12166 |
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