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Open chromatin profiling as a novel strategy for identifying cancer cell of origin

Tumor cell of origin is an important prognostic measure but is challenging to assess. We recently demonstrated in acute myeloid leukemia (AML) that the chromatin landscape serves as a biomarker of transformed cell of origin. Thus, open chromatin loci offer important prognostic information as well as...

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Detalhes bibliográficos
Publicado no:Mol Cell Oncol
Main Authors: Young, Kira, Trowbridge, Jennifer J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160412/
https://ncbi.nlm.nih.gov/pubmed/28090579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1236770
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