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Open chromatin profiling as a novel strategy for identifying cancer cell of origin

Tumor cell of origin is an important prognostic measure but is challenging to assess. We recently demonstrated in acute myeloid leukemia (AML) that the chromatin landscape serves as a biomarker of transformed cell of origin. Thus, open chromatin loci offer important prognostic information as well as...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Young, Kira, Trowbridge, Jennifer J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5160412/
https://ncbi.nlm.nih.gov/pubmed/28090579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2016.1236770
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