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Three-dimensional perfused tumour spheroid model for anti-cancer drug screening
OBJECTIVE: To build an in vitro-perfused, three-dimensional (3D) spheroid model based on the TissueFlex system for anti-cancer drug efficacy testing in order to mimic avascular micro-tissues with inherent O(2), nutrient and metabolite gradients, and to provide a more accurate prediction of drug toxi...
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| Publicado no: | Biotechnol Lett |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4942491/ https://ncbi.nlm.nih.gov/pubmed/27167883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10529-016-2035-1 |
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