Perfused Three-dimensional Organotypic Culture of Human Cancer Cells for Therapeutic Evaluation

Pharmaceutical research requires pre-clinical testing of new therapeutics using both in-vitro and in-vivo models. However, the species specificity of non-human in-vivo models and the inadequate recapitulation of physiological conditions in-vitro are intrinsic weaknesses. Here we show that perfusion...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Wan, Xiao, Ball, Steven, Willenbrock, Frances, Yeh, Shaoyang, Vlahov, Nikola, Koennig, Delia, Green, Marcus, Brown, Graham, Jeyaretna, Sanjeeva, Li, Zhaohui, Cui, Zhanfeng, Ye, Hua, O’Neill, Eric
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5573358/
https://ncbi.nlm.nih.gov/pubmed/28842598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09686-0
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