Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis

We have reported that von Hippel-Lindau protein (pVHL) expression is elevated in human and mouse fibrotic lungs and that overexpression of pVHL stimulates fibroblast proliferation. We sought to determine whether loss of pVHL in fibroblasts prevents injury and fibrosis in mice that are treated with b...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Am J Respir Cell Mol Biol
Egile Nagusiak: Zhou, Qiyuan, Chen, Tianji, Zhang, Wei, Bozkanat, Melike, Li, Yongchao, Xiao, Lei, van Breemen, Richard B., Christman, John W., Sznajder, Jacob I., Zhou, Guofei
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Thoracic Society 2016
Gaiak:
Original Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942192/
https://ncbi.nlm.nih.gov/pubmed/26488390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0111OC
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