Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis

We have reported that von Hippel-Lindau protein (pVHL) expression is elevated in human and mouse fibrotic lungs and that overexpression of pVHL stimulates fibroblast proliferation. We sought to determine whether loss of pVHL in fibroblasts prevents injury and fibrosis in mice that are treated with b...

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Bibliografiske detaljer
Udgivet i:Am J Respir Cell Mol Biol
Main Authors: Zhou, Qiyuan, Chen, Tianji, Zhang, Wei, Bozkanat, Melike, Li, Yongchao, Xiao, Lei, van Breemen, Richard B., Christman, John W., Sznajder, Jacob I., Zhou, Guofei
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2016
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942192/
https://ncbi.nlm.nih.gov/pubmed/26488390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0111OC
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