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Suppression of von Hippel-Lindau Protein in Fibroblasts Protects against Bleomycin-Induced Pulmonary Fibrosis

We have reported that von Hippel-Lindau protein (pVHL) expression is elevated in human and mouse fibrotic lungs and that overexpression of pVHL stimulates fibroblast proliferation. We sought to determine whether loss of pVHL in fibroblasts prevents injury and fibrosis in mice that are treated with b...

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Detalhes bibliográficos
Publicado no:Am J Respir Cell Mol Biol
Main Authors: Zhou, Qiyuan, Chen, Tianji, Zhang, Wei, Bozkanat, Melike, Li, Yongchao, Xiao, Lei, van Breemen, Richard B., Christman, John W., Sznajder, Jacob I., Zhou, Guofei
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4942192/
https://ncbi.nlm.nih.gov/pubmed/26488390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2015-0111OC
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