ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

Understanding mast cell development is essential due to their critical role in regulating immunity and autoimmune diseases. Here, we show how Rho kinases (ROCK) regulate mast cell development and can function as therapeutic targets for treating allergic diseases. Rock1 deficiency results in delayed...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Kapur, Reuben, Shi, Jianjian, Ghosh, Joydeep, Munugalavadla, Veerendra, Sims, Emily, Martin, Holly, Wei, Lei, Mali, Raghuveer Singh
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941361/
https://ncbi.nlm.nih.gov/pubmed/26943578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7851
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