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ROCK1 via LIM kinase regulates growth, maturation and actin based functions in mast cells

Understanding mast cell development is essential due to their critical role in regulating immunity and autoimmune diseases. Here, we show how Rho kinases (ROCK) regulate mast cell development and can function as therapeutic targets for treating allergic diseases. Rock1 deficiency results in delayed...

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Bibliografiske detaljer
Udgivet i:Oncotarget
Main Authors: Kapur, Reuben, Shi, Jianjian, Ghosh, Joydeep, Munugalavadla, Veerendra, Sims, Emily, Martin, Holly, Wei, Lei, Mali, Raghuveer Singh
Format: Artigo
Sprog:Inglês
Udgivet: Impact Journals LLC 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941361/
https://ncbi.nlm.nih.gov/pubmed/26943578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7851
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