Gamabufotalin triggers c-Myc degradation via induction of WWP2 in multiple myeloma cells

Deciding appropriate therapy for multiple myeloma (MM) is challenging because of the occurrence of multiple chromosomal changes and the fatal nature of the disease. In the current study, gamabufotalin (GBT) was isolated from toad venom, and its tumor-specific cytotoxicity was investigated in human M...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Yu, Zhenlong, Li, Tao, Wang, Chao, Deng, Sa, Zhang, Baojing, Huo, Xiaokui, Zhang, Bo, Wang, Xiaobo, Zhong, Yuping, Ma, Xiaochi
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4941272/
https://ncbi.nlm.nih.gov/pubmed/26894970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7398
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