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Inhibition of melatonin metabolism in humans induced by chemical components from herbs and effective prediction of this risk using a computational model

BACKGROUND AND PURPOSE: Herbs which are widely used as food and medicine, are involved in many physiopathological processes. Melatonin is a human hormone, synthesized and secreted by the pineal gland, with a range of biological functions. Here, we have evaluated the potential influences of component...

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Veröffentlicht in:Br J Pharmacol
Hauptverfasser: Wang, Chao, Huo, Xiaokui, Tian, Xiangge, Xu, Min, Dong, Peipei, Luan, Zhilin, Wang, Xiaobo, Zhang, Baojing, Zhang, Bo, Huang, Shanshan, Deng, Sa, Ma, Xiaochi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5071560/
https://ncbi.nlm.nih.gov/pubmed/27588415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13612
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