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From animal models to human disease: a genetic approach for personalized medicine in ALS

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Approximately 10 % of ALS patients have familial form of the disease. Numerous different gene mutati...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol Commun
Main Authors: Picher-Martel, Vincent, Valdmanis, Paul N., Gould, Peter V., Julien, Jean-Pierre, Dupré, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940869/
https://ncbi.nlm.nih.gov/pubmed/27400686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0340-5
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