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From animal models to human disease: a genetic approach for personalized medicine in ALS

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Approximately 10 % of ALS patients have familial form of the disease. Numerous different gene mutati...

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Bibliografiske detaljer
Udgivet i:Acta Neuropathol Commun
Main Authors: Picher-Martel, Vincent, Valdmanis, Paul N., Gould, Peter V., Julien, Jean-Pierre, Dupré, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4940869/
https://ncbi.nlm.nih.gov/pubmed/27400686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0340-5
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