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The use of genetically humanized animal models for personalized medicine approaches

For many genetic diseases, researchers are developing personalized medicine approaches. These sometimes employ custom genetic interventions such as antisense-mediated exon skipping or genome editing, aiming to restore protein function in a mutation-specific manner. Animal models can facilitate the d...

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Bibliografiske detaljer
Udgivet i:Dis Model Mech
Main Authors: Aartsma-Rus, Annemieke, van Putten, Maaike
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6906630/
https://ncbi.nlm.nih.gov/pubmed/31591145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.041673
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