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Inclusion of Strep-Tag II in design of antigen receptors for T cell immunotherapy
The tactical introduction of Strep-tag II into synthetic antigen receptors provides engineered T cells with a marker for identification and rapid purification, and a functional element for selective antibody coated microbead-driven large-scale expansion. Such receptor designs can be applied to chime...
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| Publicado no: | Nat Biotechnol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940167/ https://ncbi.nlm.nih.gov/pubmed/26900664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nbt.3461 |
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