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Thousands of novel translated open reading frames in humans inferred by ribosome footprint profiling
Accurate annotation of protein coding regions is essential for understanding how genetic information is translated into function. We describe riboHMM, a new method that uses ribosome footprint data to accurately infer translated sequences. Applying riboHMM to human lymphoblastoid cell lines, we iden...
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| Veröffentlicht in: | eLife |
|---|---|
| Hauptverfasser: | , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4940163/ https://ncbi.nlm.nih.gov/pubmed/27232982 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.13328 |
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