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msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding

Understanding global gene regulation depends critically on accurate annotation of regulatory elements that are functional in a given cell type. CENTIPEDE, a powerful, probabilistic framework for identifying transcription factor binding sites from tissue-specific DNase I cleavage patterns and genomic...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Raj, Anil, Shim, Heejung, Gilad, Yoav, Pritchard, Jonathan K., Stephens, Matthew
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583425/
https://ncbi.nlm.nih.gov/pubmed/26406244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138030
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