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msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding

Understanding global gene regulation depends critically on accurate annotation of regulatory elements that are functional in a given cell type. CENTIPEDE, a powerful, probabilistic framework for identifying transcription factor binding sites from tissue-specific DNase I cleavage patterns and genomic...

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Vydáno v:PLoS One
Hlavní autoři: Raj, Anil, Shim, Heejung, Gilad, Yoav, Pritchard, Jonathan K., Stephens, Matthew
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583425/
https://ncbi.nlm.nih.gov/pubmed/26406244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138030
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