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msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding

Understanding global gene regulation depends critically on accurate annotation of regulatory elements that are functional in a given cell type. CENTIPEDE, a powerful, probabilistic framework for identifying transcription factor binding sites from tissue-specific DNase I cleavage patterns and genomic...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Raj, Anil, Shim, Heejung, Gilad, Yoav, Pritchard, Jonathan K., Stephens, Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583425/
https://ncbi.nlm.nih.gov/pubmed/26406244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138030
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