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msCentipede: Modeling Heterogeneity across Genomic Sites and Replicates Improves Accuracy in the Inference of Transcription Factor Binding

Understanding global gene regulation depends critically on accurate annotation of regulatory elements that are functional in a given cell type. CENTIPEDE, a powerful, probabilistic framework for identifying transcription factor binding sites from tissue-specific DNase I cleavage patterns and genomic...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Raj, Anil, Shim, Heejung, Gilad, Yoav, Pritchard, Jonathan K., Stephens, Matthew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583425/
https://ncbi.nlm.nih.gov/pubmed/26406244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138030
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