Nanoparticle-Mediated Delivery of Irbesartan Induces Cardioprotection from Myocardial Ischemia-Reperfusion Injury by Antagonizing Monocyte-Mediated Inflammation

Myocardial ischemia-reperfusion (IR) injury limits the therapeutic effect of early reperfusion therapy for acute myocardial infarction (AMI), in which the recruitment of inflammatory monocytes plays a causative role. Here we develop bioabsorbable poly-lactic/glycolic acid (PLGA) nanoparticles incorp...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Nakano, Yasuhiro, Matoba, Tetsuya, Tokutome, Masaki, Funamoto, Daiki, Katsuki, Shunsuke, Ikeda, Gentaro, Nagaoka, Kazuhiro, Ishikita, Ayako, Nakano, Kaku, Koga, Jun-ichiro, Sunagawa, Kenji, Egashira, Kensuke
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4939605/
https://ncbi.nlm.nih.gov/pubmed/27403534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29601
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