CRISPR/Cas9-Mediated Insertion of loxP Sites in the Mouse Dock7 Gene Provides an Effective Alternative to Use of Targeted Embryonic Stem Cells

Targeted gene mutation in the mouse is a primary strategy to understand gene function and relation to phenotype. The Knockout Mouse Project (KOMP) had an initial goal to develop a public resource of mouse embryonic stem (ES) cell clones that carry null mutations in all genes. Indeed, many useful nov...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Bishop, Kathleen A., Harrington, Anne, Kouranova, Evguenia, Weinstein, Edward J., Rosen, Clifford J., Cui, Xiaoxia, Liaw, Lucy
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2016
Assuntos:
Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4938658/
https://ncbi.nlm.nih.gov/pubmed/27175020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.030601
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados