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Tumor-infiltrating HLA-matched CD4(+) T cells retargeted against Hodgkin and Reed–Sternberg cells
Hodgkin lymphoma (HL) presents with a unique histologic pattern. Pathognomonic Hodgkin and Reed–Sternberg (HRS) cells usually account for less than 1% of the tumor and are embedded in a reactive infiltrate mainly comprised of CD4(+) T cells. HRS cells induce an immunosuppressive microenvironment and...
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| 出版年: | Oncoimmunology |
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| 主要な著者: | , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Taylor & Francis
2016
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4938355/ https://ncbi.nlm.nih.gov/pubmed/27471632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2016.1160186 |
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