Small and big Hodgkin-Reed-Sternberg cells of Hodgkin lymphoma cell lines L-428 and L-1236 lack consistent differences in gene expression profiles and are capable to reconstitute each other

The hallmark of classical Hodgkin lymphoma (cHL) is the presence of giant, mostly multinucleated Hodgkin-Reed-Sternberg (HRS) cells. Whereas it has recently been shown that giant HRS cells evolve from small Hodgkin cells by incomplete cytokinesis and re-fusion of tethered sister cells, it remains un...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Rengstl, Benjamin, Kim, Sooji, Döring, Claudia, Weiser, Christian, Bein, Julia, Bankov, Katrin, Herling, Marco, Newrzela, Sebastian, Hansmann, Martin-Leo, Hartmann, Sylvia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5432067/
https://ncbi.nlm.nih.gov/pubmed/28505189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0177378
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