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Emerging concepts for PI3K/mTOR inhibition as a potential treatment for osteosarcoma

Patients with metastatic and recurrent osteosarcoma fare poorly, and new therapeutic strategies are needed to improve survival. Several recent complementary genomic and pathway analyses of both murine and human osteosarcoma have revealed common aberrations of the phosphoinositide 3-kinase (PI3K)/mam...

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Détails bibliographiques
Publié dans:F1000Res
Auteurs principaux: Bishop, Michael W., Janeway, Katherine A.
Format: Artigo
Langue:Inglês
Publié: F1000Research 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937817/
https://ncbi.nlm.nih.gov/pubmed/27441088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.8228.1
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