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Emerging concepts for PI3K/mTOR inhibition as a potential treatment for osteosarcoma

Patients with metastatic and recurrent osteosarcoma fare poorly, and new therapeutic strategies are needed to improve survival. Several recent complementary genomic and pathway analyses of both murine and human osteosarcoma have revealed common aberrations of the phosphoinositide 3-kinase (PI3K)/mam...

詳細記述

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書誌詳細
出版年:F1000Res
主要な著者: Bishop, Michael W., Janeway, Katherine A.
フォーマット: Artigo
言語:Inglês
出版事項: F1000Research 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937817/
https://ncbi.nlm.nih.gov/pubmed/27441088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.8228.1
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