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Emerging concepts for PI3K/mTOR inhibition as a potential treatment for osteosarcoma

Patients with metastatic and recurrent osteosarcoma fare poorly, and new therapeutic strategies are needed to improve survival. Several recent complementary genomic and pathway analyses of both murine and human osteosarcoma have revealed common aberrations of the phosphoinositide 3-kinase (PI3K)/mam...

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Dades bibliogràfiques
Publicat a:F1000Res
Autors principals: Bishop, Michael W., Janeway, Katherine A.
Format: Artigo
Idioma:Inglês
Publicat: F1000Research 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937817/
https://ncbi.nlm.nih.gov/pubmed/27441088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.8228.1
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