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The effect of leaving groups on binding and reactivity in enzyme-free copying of DNA and RNA
The template-directed incorporation of nucleotides at the terminus of a growing primer is the basis of the transmission of genetic information. Nature uses polymerases-catalyzed reactions, but enzyme-free versions exist that employ nucleotides with organic leaving groups. The leaving group affects y...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4937335/ https://ncbi.nlm.nih.gov/pubmed/27235418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw476 |
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