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2′/3′ Regioselectivity of Enzyme‐Free Copying of RNA Detected by NMR

The RNA‐templated extension of oligoribonucleotides by nucleotides produces either a 3′,5′ or a 2′,5′‐phosphodiester. Nature controls the regioselectivity during RNA chain growth with polymerases, but enzyme‐free versions of genetic copying have modest specificity. Thus far, enzymatic degradation of...

詳細記述

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書誌詳細
出版年:Chembiochem
主要な著者: Motsch, Sebastian, Pfeffer, Daniel, Richert, Clemens
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497262/
https://ncbi.nlm.nih.gov/pubmed/32017335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.202000014
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