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Cascade of Reduced Speed and Accuracy After Errors in Enzyme-Free Copying of Nucleic Acid Sequences

Non-enzymatic, template-directed synthesis of nucleic acids is a paradigm for self-replicating systems. The evolutionary dynamics of such systems depend on several factors, including the mutation rates, relative replication rates, and sequence characteristics of mutant sequences. We measured the kin...

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Bibliografski detalji
Glavni autori: Leu, Kevin, Kervio, Eric, Obermayer, Benedikt, Turk-MacLeod, Rebecca M., Yuan, Caterina, Luevano, Jesus-Mario, Chen, Eric, Gerland, Ulrich, Richert, Clemens, Chen, Irene A.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3557965/
https://ncbi.nlm.nih.gov/pubmed/23259600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja3095558
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