Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system

Shewanella putrefaciens CN-32 contains a single Type I-Fv CRISPR-Cas system which confers adaptive immunity against bacteriophage infection. Three Cas proteins (Cas6f, Cas7fv, Cas5fv) and mature CRISPR RNAs were shown to be required for the assembly of an interference complex termed Cascade. The Cas...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Gleditzsch, Daniel, Müller-Esparza, Hanna, Pausch, Patrick, Sharma, Kundan, Dwarakanath, Srivatsa, Urlaub, Henning, Bange, Gert, Randau, Lennart
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
Nucleic Acid Enzymes
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937334/
https://ncbi.nlm.nih.gov/pubmed/27216815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw469
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