Modulating the Cascade architecture of a minimal Type I-F CRISPR-Cas system

Shewanella putrefaciens CN-32 contains a single Type I-Fv CRISPR-Cas system which confers adaptive immunity against bacteriophage infection. Three Cas proteins (Cas6f, Cas7fv, Cas5fv) and mature CRISPR RNAs were shown to be required for the assembly of an interference complex termed Cascade. The Cas...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Gleditzsch, Daniel, Müller-Esparza, Hanna, Pausch, Patrick, Sharma, Kundan, Dwarakanath, Srivatsa, Urlaub, Henning, Bange, Gert, Randau, Lennart
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Nucleic Acid Enzymes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937334/
https://ncbi.nlm.nih.gov/pubmed/27216815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw469
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