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Plk1 inhibitors in cancer therapy: From laboratory to clinics

Polo-like kinase 1 (Plk1) overexpression has been shown to occur in a wide range of tumors, prompting research and development of Plk1 inhibitors as a means of cancer treatment. This review discusses recent advances in the development of Plk1 inhibitors for cancer management. Plk1 inhibition has bee...

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Publicado en:Mol Cancer Ther
Autores principales: Gutteridge, Rosie Elizabeth Ann, Ndiaye, Mary Ann, Liu, Xiaoqi, Ahmad, Nihal
Formato: Artigo
Lenguaje:Inglês
Publicado: 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936921/
https://ncbi.nlm.nih.gov/pubmed/27330107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-15-0897
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