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Osteopontin is associated with inflammation and mortality in a mouse model of polymicrobial sepsis
BACKGROUND: Osteopontin (OPN) is a multifunctional glycoprotein with pro-inflammatory properties. In severe sepsis, levels of plasma OPN are significantly higher in non-survivors than in survivors. We hypothesized that OPN results in greater inflammation and worse outcome through modulation of endog...
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| Publicado no: | Acta Anaesthesiol Scand |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4936904/ https://ncbi.nlm.nih.gov/pubmed/25328143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/aas.12422 |
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