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Nonhematopoietic β-Arrestin-1 Inhibits Inflammation in a Murine Model of Polymicrobial Sepsis

β-Arrestin-1 (βArr1), a scaffolding protein critical in G-protein coupled receptor desensitization has more recently been found to be important in the pathogenesis of various inflammatory diseases. We sought to understand the role of βArr1 in sepsis pathogenesis using a mouse model of polymicrobial...

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Hlavní autoři: Sharma, Deepika, Packiriswamy, Nandakumar, Malik, Ankit, Lucas, Peter C., Parameswaran, Narayanan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116700/
https://ncbi.nlm.nih.gov/pubmed/24946011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.05.002
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