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Nonhematopoietic β-Arrestin-1 Inhibits Inflammation in a Murine Model of Polymicrobial Sepsis

β-Arrestin-1 (βArr1), a scaffolding protein critical in G-protein coupled receptor desensitization has more recently been found to be important in the pathogenesis of various inflammatory diseases. We sought to understand the role of βArr1 in sepsis pathogenesis using a mouse model of polymicrobial...

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Detalhes bibliográficos
Main Authors: Sharma, Deepika, Packiriswamy, Nandakumar, Malik, Ankit, Lucas, Peter C., Parameswaran, Narayanan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116700/
https://ncbi.nlm.nih.gov/pubmed/24946011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2014.05.002
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