CD40 and CD80/86 Act Synergistically to Regulate Inflammation and Mortality in Polymicrobial Sepsis

Rationale: Costimulatory molecules, including the CD40–CD154 and CD80/86–CD28 dyads, play a prominent role in regulating inflammation in the adaptive immune response. Studies from our group and others suggest a potentially important role for these costimulatory cascades in innate immunity as well. O...

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Main Authors: Nolan, Anna, Weiden, Michael, Kelly, Ann, Hoshino, Yoshihiko, Hoshino, Satomi, Mehta, Nehal, Gold, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2008
Assuntos:
D. Critical Care
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2218847/
https://ncbi.nlm.nih.gov/pubmed/17989345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200703-515OC
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