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Vascular Endothelial Growth Factor Blockade Reduces Plasma Cytokines in a Murine Model of Polymicrobial Sepsis

Numerous cytokines, including vascular endothelial growth factor (VEGF), are implicated in the pathogenesis of sepsis. While overexpression of VEGF produces pulmonary capillary leak, the role of VEGF in sepsis is less clear. We investigated VEGF in sepsis, utilizing a VEGF trap (VEGF(T)). Polymicrob...

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Detalhes bibliográficos
Main Authors: Nolan, Anna, Weiden, Michael D., Thurston, Gavin, Gold, Jeffrey A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417046/
https://ncbi.nlm.nih.gov/pubmed/16134000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10753-004-6050-3
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