The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

BACKGROUND: In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical...

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Vydáno v:PLoS Negl Trop Dis
Hlavní autoři: Hess, Jessica A., Zhan, Bin, Torigian, April R., Patton, John B., Petrovsky, Nikolai, Zhan, Tingting, Bottazzi, Maria Elena, Hotez, Peter J., Klei, Thomas R., Lustigman, Sara, Abraham, David
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936747/
https://ncbi.nlm.nih.gov/pubmed/27387453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004797
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