Development of Onchocerca volvulus in humanized NSG mice and detection of parasite biomarkers in urine and serum

BACKGROUND: The study of Onchocerca volvulus has been limited by its host range, with only humans and non-human primates shown to be susceptible to the full life cycle infection. Small animal models that support the development of adult parasites have not been identified. METHODOLOGY/PRINCIPAL FINDI...

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Pubblicato in:PLoS Negl Trop Dis
Autori principali: Patton, John B., Bennuru, Sasisekhar, Eberhard, Mark L., Hess, Jessica A., Torigian, April, Lustigman, Sara, Nutman, Thomas B., Abraham, David
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6306240/
https://ncbi.nlm.nih.gov/pubmed/30540742
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006977
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