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The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice

BACKGROUND: In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical...

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Bibliografske podrobnosti
izdano v:PLoS Negl Trop Dis
Main Authors: Hess, Jessica A., Zhan, Bin, Torigian, April R., Patton, John B., Petrovsky, Nikolai, Zhan, Tingting, Bottazzi, Maria Elena, Hotez, Peter J., Klei, Thomas R., Lustigman, Sara, Abraham, David
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936747/
https://ncbi.nlm.nih.gov/pubmed/27387453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0004797
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