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The Immunomodulatory Role of Adjuvants in Vaccines Formulated with the Recombinant Antigens Ov-103 and Ov-RAL-2 against Onchocerca volvulus in Mice.

BACKGROUND:In some regions in Africa, elimination of onchocerciasis may be possible with mass drug administration, although there is concern based on several factors that onchocerciasis cannot be eliminated solely through this approach. A vaccine against Onchocerca volvulus would provide a critical...

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Detalhes bibliográficos
Main Authors: Jessica A Hess, Bin Zhan, April R Torigian, John B Patton, Nikolai Petrovsky, Tingting Zhan, Maria Elena Bottazzi, Peter J Hotez, Thomas R Klei, Sara Lustigman, David Abraham
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2016-07-01
Colecção:PLoS Neglected Tropical Diseases
Acesso em linha:http://europepmc.org/articles/PMC4936747?pdf=render
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