The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis

Mitochondria must buffer the risk of proteotoxic stress to preserve bioenergetics, but the role of these mechanisms in disease is poorly understood. Using a proteomics screen, we now show that the mitochondrial unfoldase-peptidase complex ClpXP associates with the oncoprotein survivin and the respir...

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Detalhes bibliográficos
Publicado no:PLoS Biol
Main Authors: Seo, Jae Ho, Rivadeneira, Dayana B., Caino, M. Cecilia, Chae, Young Chan, Speicher, David W., Tang, Hsin-Yao, Vaira, Valentina, Bosari, Silvano, Palleschi, Alessandro, Rampini, Paolo, Kossenkov, Andrew V., Languino, Lucia R., Altieri, Dario C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4936714/
https://ncbi.nlm.nih.gov/pubmed/27389535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1002507
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